Semax/Selank is a synthetic peptide blend meticulously prepared for scientific inquiry. This product, combining Semax and Selank, is synthesized with high purity for laboratory investigations. It is developed for use in various research applications. Semax/Selank is designated solely for research and development purposes.
Semax features the sequence Met-Glu-His-Phe-Pro-Gly-Pro, a stable analog of ACTH(4-10) with a molecular weight of approximately 813 Da, known for its resistance to enzymatic degradation and ability to cross the blood-brain barrier in models. Selank, on the other hand, has the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, with a molecular weight around 751 Da, drawing from the immunomodulatory peptide tuftsin while incorporating modifications for enhanced stability and bioavailability. When combined, these peptides maintain their individual profiles but may interact in ways that support mutual efficacy, as seen in functional connectivity studies.
In lab practice, our Semax/Selank blend is provided as a lyophilized powder mixture, with each component verified for purity exceeding 98% via HPLC and mass spectrometry. The combination exhibits good solubility in neutral aqueous buffers, though careful pH monitoring is advised to preserve structural integrity. Our rigorous testing ensures batch consistency, allowing you to explore their interplay without variability concerns—we're committed to transparency every step of the way.
The Semax/Selank combination brings together two synthetic heptapeptides—Semax, an analog of adrenocorticotropin (ACTH 4-10), and Selank, a tuftsin derivative—each with distinct neuroprotective and anxiolytic properties, offering researchers a synergistic tool for exploring brain function, stress response, and cognitive modulation in in-vitro models. This blend is designed to leverage Semax's neurotrophic effects alongside Selank's immunomodulatory and calming influences, potentially amplifying outcomes in studies of neural resilience and behavioral adaptation. As with all our peptides, the Semax/Selank combination is supplied exclusively for research purposes and in-vitro use only—not for human consumption or any clinical applications.
Semax primarily enhances brain-derived neurotrophic factor (BDNF) expression and modulates gene activity related to vascular and neural repair, particularly in ischemic conditions, by influencing transcription factors and promoting neuroplasticity. Selank, meanwhile, exerts anxiolytic effects by altering neurotransmitter gene expression, enhancing GABAergic signaling, and reducing inflammatory cytokines, often amplifying the actions of benzodiazepines without direct receptor binding. In combination, these peptides may synergize to modulate resting-state brain connectivity, potentially balancing neurotrophic support with stress attenuation for broader neuroprotective outcomes.
This dual action could involve shared melanocortin pathways, where Semax's copper-chelating properties complement Selank's anti-stress mechanisms, fostering resilience against oxidative and inflammatory challenges. We find it fascinating how such pairings illuminate cellular crosstalk, and we're eager to help you design assays that tease apart these interactions logically.
In wrapping up, the Semax/Selank combination provides a thoughtful fusion of neurotrophic and anxiolytic peptides, enabling researchers to delve into integrated mechanisms of neural protection, stress modulation, and cognitive support in refined in-vitro settings. Though our understanding evolves, its potential synergies excite our shared pursuit of peptide science through quality and education. Strictly for research use, this blend underscores our dedication to transparent, approachable tools that advance discovery. Let's collaborate to explore further, one steady experiment at a time.
The Semax/Selank combination shines in in-vitro and ex-vivo models investigating neurodegenerative conditions, stress-related disorders, and cognitive enhancement. In ischemia simulations, Semax's role in upregulating neurotrophins pairs with Selank's cytokine modulation to probe enhanced recovery and reduced inflammation in neural cultures. Studies on Parkinson's-like models have explored their combined behavioral impacts, suggesting potential in alleviating motor and cognitive deficits through gene expression changes.
Researchers have also applied this blend to anxiety and withdrawal paradigms, where Selank's psychostimulant effects complement Semax's nootropic actions, as seen in ethanol exposure models protecting memory and reducing asthenia. Emerging work in functional connectomics highlights how the duo alters brain network patterns, useful for mapping stress resilience in isolated systems. We recommend it for gene expression assays or synaptic plasticity studies, and our team can offer insights on ratios to optimize for your specific endpoints—always with a focus on ethical, controlled research.
For the best results with our Semax/Selank combination, store the lyophilized powder at -20°C or below in a desiccated, light-protected container to maintain stability for both peptides. Reconstitute with sterile bacteriostatic water or a neutral buffer to achieve concentrations of 1-2 mg/mL per component, gently mixing to avoid denaturation—vigorous agitation might compromise their structures.
Once prepared, aliquot solutions and use fresh, storing at 2-8°C for short-term or freezing for extended periods, while minimizing freeze-thaw cycles. Our quality controls include stability testing for the blend, but check for clarity and pH neutrality before assays. If you need tailored advice on handling this combo, we're here with practical, evidence-based suggestions.
The Semax/Selank combination brings together two synthetic heptapeptides—Semax, an analog of adrenocorticotropin (ACTH 4-10), and Selank, a tuftsin derivative—each with distinct neuroprotective and anxiolytic properties, offering researchers a synergistic tool for exploring brain function, stress response, and cognitive modulation in in-vitro models. This blend is designed to leverage Semax's neurotrophic effects alongside Selank's immunomodulatory and calming influences, potentially amplifying outcomes in studies of neural resilience and behavioral adaptation. As with all our peptides, the Semax/Selank combination is supplied exclusively for research purposes and in-vitro use only—not for human consumption or any clinical applications.
Semax primarily enhances brain-derived neurotrophic factor (BDNF) expression and modulates gene activity related to vascular and neural repair, particularly in ischemic conditions, by influencing transcription factors and promoting neuroplasticity. Selank, meanwhile, exerts anxiolytic effects by altering neurotransmitter gene expression, enhancing GABAergic signaling, and reducing inflammatory cytokines, often amplifying the actions of benzodiazepines without direct receptor binding. In combination, these peptides may synergize to modulate resting-state brain connectivity, potentially balancing neurotrophic support with stress attenuation for broader neuroprotective outcomes.
This dual action could involve shared melanocortin pathways, where Semax's copper-chelating properties complement Selank's anti-stress mechanisms, fostering resilience against oxidative and inflammatory challenges. We find it fascinating how such pairings illuminate cellular crosstalk, and we're eager to help you design assays that tease apart these interactions logically.
In wrapping up, the Semax/Selank combination provides a thoughtful fusion of neurotrophic and anxiolytic peptides, enabling researchers to delve into integrated mechanisms of neural protection, stress modulation, and cognitive support in refined in-vitro settings. Though our understanding evolves, its potential synergies excite our shared pursuit of peptide science through quality and education. Strictly for research use, this blend underscores our dedication to transparent, approachable tools that advance discovery. Let's collaborate to explore further, one steady experiment at a time.
Semax features the sequence Met-Glu-His-Phe-Pro-Gly-Pro, a stable analog of ACTH(4-10) with a molecular weight of approximately 813 Da, known for its resistance to enzymatic degradation and ability to cross the blood-brain barrier in models. Selank, on the other hand, has the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, with a molecular weight around 751 Da, drawing from the immunomodulatory peptide tuftsin while incorporating modifications for enhanced stability and bioavailability. When combined, these peptides maintain their individual profiles but may interact in ways that support mutual efficacy, as seen in functional connectivity studies.
In lab practice, our Semax/Selank blend is provided as a lyophilized powder mixture, with each component verified for purity exceeding 98% via HPLC and mass spectrometry. The combination exhibits good solubility in neutral aqueous buffers, though careful pH monitoring is advised to preserve structural integrity. Our rigorous testing ensures batch consistency, allowing you to explore their interplay without variability concerns—we're committed to transparency every step of the way.
The Semax/Selank combination shines in in-vitro and ex-vivo models investigating neurodegenerative conditions, stress-related disorders, and cognitive enhancement. In ischemia simulations, Semax's role in upregulating neurotrophins pairs with Selank's cytokine modulation to probe enhanced recovery and reduced inflammation in neural cultures. Studies on Parkinson's-like models have explored their combined behavioral impacts, suggesting potential in alleviating motor and cognitive deficits through gene expression changes.
Researchers have also applied this blend to anxiety and withdrawal paradigms, where Selank's psychostimulant effects complement Semax's nootropic actions, as seen in ethanol exposure models protecting memory and reducing asthenia. Emerging work in functional connectomics highlights how the duo alters brain network patterns, useful for mapping stress resilience in isolated systems. We recommend it for gene expression assays or synaptic plasticity studies, and our team can offer insights on ratios to optimize for your specific endpoints—always with a focus on ethical, controlled research.
For the best results with our Semax/Selank combination, store the lyophilized powder at -20°C or below in a desiccated, light-protected container to maintain stability for both peptides. Reconstitute with sterile bacteriostatic water or a neutral buffer to achieve concentrations of 1-2 mg/mL per component, gently mixing to avoid denaturation—vigorous agitation might compromise their structures.
Once prepared, aliquot solutions and use fresh, storing at 2-8°C for short-term or freezing for extended periods, while minimizing freeze-thaw cycles. Our quality controls include stability testing for the blend, but check for clarity and pH neutrality before assays. If you need tailored advice on handling this combo, we're here with practical, evidence-based suggestions.
